Gefitinib

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Cat Number

API184475352

CAS Number

184475-35-2

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Product Detail

CAS Number

184475-35-2

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation.

Molecular Formula

C22H24ClFN4O3

Molecular Weight

446.9

Smiles

N(C=1C2=C(C=C(OC)C(OCCCN3CCOCC3)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4

Relative Density

1.322

Purity

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