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Cat Number: API1454846355

Lorlatinib

CAS Number

1454846-35-5

Description

Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity.

Molecular Formula

C21H19FN6O2

Molecular Weight

406.41

Smiles

C[C@H]1OC2CC(CNC2N)-C2C(CN(C)C(=O)C3CCC(F)CC13)NN(C)C2C#N

Purity

0.9982

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

Ethanol: 40.6 mg/mL (100 mM)DMSO: 15 mg/mL (36.91 mM), Sonication is recommended.

Relative Density

1.42 (Predicted)

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