Synonyms
Transforming Growth Factor alpha; TGF-a; TGF-type I; ETGF
Description
Transforming Growth Factor-alpha (TGF-α) , also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells.Mature TGF-alpha shows approximately 93% amino acid sequence identity with mouse or rat TGF-alpha and is not species specific in its biological effects.
Molecular Weight
Approximately 5.8 kDa, on SDS-PAGE under reducing conditions.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
> 95% as determined by SDS-PAGE