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2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile

2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile

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Cat Number
INT1401031386
CAS Number
1401031-38-6

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CAS Number
1401031-38-6
Storage
2-8℃
Synonyms
(R)-2-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetonitrile;2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitril
Molecular Formula
C16H20N2O
Molecular Weight
256.34
Smiles
C1C2(C[C@@](C3=NC=CC=C3)(CC#N)CCO2)CCC1
Appearance
White to off-white solid
Melting Point
110 - 112℃
Boiling Point
445.3℃
Relative Density
1.13
pKa
5.41
General Description
2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile is a chiral primary amine featuring a pyridine ring attached to a spirocyclic oxaspirodecane system. It is a highly specialized pharmaceutical intermediate. dec-9-yl]ethanamine]
Mechanism of Action
It functions as a rigid heterocyclic building block. The (9R) configuration is critical for the precise positioning of the amine and pyridine groups, which is required for high-affinity binding to target receptors.
Application
It is a critical intermediate in the final synthesis of Oliceridine and related selective opioid receptor modulators.

Is 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile chiral?

Yes, it is produced as the (9R) enantiomer for specific therapeutic use.

What is the role of 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile?

It acts as a key building block for Oliceridine synthesis.

How to store 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile?

It should be kept in a dry, cool place protected from light.

Does 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile meet industry standards?

Yes, it is produced according to international standards for high-purity chemicals.

Are SDS available for 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile?

Yes, we provide a detailed SDS for it upon request.

Is the purity of 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile verified?

Yes, we confirm its purity and optical rotation via HPLC and polarimetry.
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