Cat Number: API177325132

Levofloxacin hydrochloride

APIs
CAS Number
177325-13-2
Description
Levofloxacin is a broad-spectrum,third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II),an enzyme required for DNA replication,RNA transcription,and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.
Molecular Formula
C18H21ClFN3O4
Molecular Weight
397.8
Smiles
Cl.C[C@H]1COC2C(N3CCN(C)CC3)C(F)CC3C2N1CC(C(O)=O)C3=O
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 7.14 mg/mL (17.96 mM), Sonication is recommended.H2O: 100 mg/mL (251.38 mM)
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