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Cabozantinib

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Cat Number

API849217681

CAS Number

849217-68-1

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Product Detail

CAS Number

849217-68-1

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity.

Molecular Formula

C28H24FN3O5

Molecular Weight

501.51

Smiles

C(NC1=CC=C(OC=2C3=C(C=C(OC)C(OC)=C3)N=CC2)C=C1)(=O)C4(C(NC5=CC=C(F)C=C5)=O)CC4

Relative Density

1.397

Purity

0.9988

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