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Rucaparib hydrochloride

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Cat Number
API773059191
CAS Number
773059-19-1

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CAS Number
773059-19-1
Description
Rucaparib hydrochloride, also known as AG014699, is a powerful and orally active compound that inhibits PARP proteins including PARP-1, PARP-2, and PARP-3 with a Ki value of 1.4 nM for PARP1. Additionally, Rucaparib hydrochloride acts as a modest inhibitor of hexose-6-phosphate dehydrogenase (H6PD). This compound shows potential in research for castration-resistant prostate cancer (CRPC).
Molecular Formula
C19H19ClFN3O
Molecular Weight
359.83
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