Cat Number: API1621884227

PSI-7409 tetrasodium

APIs
CAS Number
1621884-22-7
Description
PSI-7409 tetrasodium, the active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), exhibits specific inhibitory activity against NS5B polymerases of various genotypes, with IC50s being 1.6 μM for GT 1b_Con1, 2.8 μM for GT 2a_JFH1, 0.7 μM for GT 3a, and 2.6 μM for GT 4a, respectively.
Molecular Formula
C10H16FN2Na4O14P3
Molecular Weight
592.117
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
H2O: 125 mg/mL (211.11 mM)
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