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PSI-7409 tetrasodium

PSI-7409 tetrasodium

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Cat Number
API1621884227
CAS Number
1621884-22-7

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CAS Number
1621884-22-7
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Description
PSI-7409 tetrasodium, the active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), exhibits specific inhibitory activity against NS5B polymerases of various genotypes, with IC50s being 1.6 μM for GT 1b_Con1, 2.8 μM for GT 2a_JFH1, 0.7 μM for GT 3a, and 2.6 μM for GT 4a, respectively.
Molecular Formula
C10H16FN2Na4O14P3
Molecular Weight
592.117
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