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Trilostane

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Cat Number

API13647353

CAS Number

13647-35-3

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Product Detail

CAS Number

13647-35-3

EINECS

237-133-0

Synonyms

Modrenal, Vetoryl, Desopan

Description

Trilostane is a synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex, resulting in the decreased synthesis of mineralocorticoids and glucocorticoids and the decreased conversion of pregnenolone to progesterone.

Molecular Formula

C20H27NO3

Molecular Weight

329.4

Smiles

CC12CCC3C(C1CCC2O)CCC45C3(CC(=C(C4O5)O)C#N)C

Appearance

Yellow-brown Crystalline Solid

Melting Point

264dec ℃

Boiling Point

516.5℃ at 760 mmHg