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Trilostane

Trilostane

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Cat Number
API13647353
CAS Number
13647-35-3

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CAS Number
13647-35-3
EINECS
237-133-0
Synonyms
Modrenal, Vetoryl, Desopan
Description
Trilostane is a synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex, resulting in the decreased synthesis of mineralocorticoids and glucocorticoids and the decreased conversion of pregnenolone to progesterone.
Molecular Formula
C20H27NO3
Molecular Weight
329.4
Smiles
CC12CCC3C(C1CCC2O)CCC45C3(CC(=C(C4O5)O)C#N)C
Appearance
Yellow-brown Crystalline Solid
Melting Point
264dec ℃
Boiling Point
516.5℃ at 760 mmHg
Relative Density
1.1213
Standard
Facility GMP
Qualification
USDMF