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Cat Number: API1290543633

Nirogacestat

CAS Number

1290543-63-3

Synonyms

PF-3084014

Description

Nirogacestat is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor with an IC50 of 6.2 nM.

Molecular Formula

C27H41F2N5O

Molecular Weight

489.64

Smiles

FC1=C2C(CC[C@H](N[C@@H](CCC)C(NC3=CN(C(C)(C)CNCC(C)(C)C)C=N3)=O)C2)=CC(F)=C1

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