Metrizoate Sodium

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Cat Number

API7225618

CAS Number

7225-61-8

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Product Detail Description Customer Q&A

CAS Number

7225-61-8

EINECS

230-624-0

Synonyms

3-Acetylamino-2,4,6-triiodo-5-(N-methylacetylamino)benzoic acid sodium

Molecular Formula

C12H10I3N2NaO4

Molecular Weight

649.92

Smiles

CC(=O)NC1=C(C(=C(C(=C1I)C(=O)[O-])I)N(C)C(=O)C)I.[Na+]

General Description

Metrizoate Sodium is a radiopaque iodinated contrast agent of the ionic monomer type, containing three iodine atoms per molecule. Structurally related to diatrizoate (hypaque), it is used as an injectable contrast medium for radiographic procedures including cardioangiography, cerebral angiography, and urography. Its high iodine content provides excellent X-ray attenuation.

Mechanism of Action

Metrizoate Sodium acts as an extracellular iodinated contrast agent. Its radiodensity (opacity to X-rays) is directly proportional to its iodine concentration, attenuating X-ray beams as they pass through vascular and tissue structures, thereby creating contrast on radiographic images. As an ionic, high-osmolality contrast medium (HOCM), it causes dose-dependent effects on blood viscosity, endothelial function, cardiac conduction, and renal perfusion.

Application

Metrizoate Sodium is indicated as a contrast medium for intravascular administration in cardioangiography (coronary and ventricular angiography), cerebral angiography, peripheral angiography, urography, and contrast-enhanced computed tomography.

What is the recommended storage condition for Metrizoate Sodium?

It should be stored at controlled room temperature in a well-sealed container, protected from moisture and direct light, to maintain its chemical integrity throughout the shelf life.

Can we obtain batch-specific analytical data for Metrizoate Sodium?

Batch-specific COA documents are standard with every shipment. Additional analytical reports, including HPLC chromatograms or spectral data, may be provided upon request.

What is the minimum order quantity (MOQ) for Metrizoate Sodium?

Flexible MOQ options are available to support both early-stage research and large-scale manufacturing needs. Our team can tailor order quantities to match your specific requirements.

Does Metrizoate Sodium have pharmacopoeial monograph compliance?

Material meeting applicable pharmacopoeial specifications or equivalent internal quality standards can be supplied; please contact us with your specific compendial requirements.