Iocetamic Acid

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Cat Number

API16034778

CAS Number

16034-77-8

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Product Detail Description Customer Q&A

CAS Number

16034-77-8

EINECS

240-173-1

Synonyms

3-(N-(3-Amino-2,4,6-triiodophenyl)acetamido)-2-methylpropanoic acid;3-[Acetyl(3-amino-2,4,6-triiodophenyl)amino]-2-methylpropionic acid;n-acetyl-n-(3-amino-2,4,6-triiodophenl)-2-methyl-beta-alanine

Molecular Formula

C12H13I3N2O3

Molecular Weight

613.96

Smiles

CC(CN(C1=C(C=C(C(=C1I)N)I)I)C(=O)C)C(=O)O

Melting Point

224-225℃

Boiling Point

658.2℃

Relative Density

2.2

pKa

General Description

Iocetamic Acid is an ionic triiodobenzene radiographic contrast agent designed for oral cholecystography. It is selectively absorbed from the intestine and excreted into the biliary system.

Mechanism of Action

Iocetamic Acid absorbs X-rays through its three iodine atoms per molecule, enhancing radiographic contrast. After oral absorption, it is transported to the liver and excreted into bile, concentrating in the gallbladder for visualization.

Application

Used in diagnostic cholecystography. Iocetamic Acid is indicated for radiographic visualization of the gallbladder and biliary tree to detect gallstones, cholecystitis, and biliary obstruction.

What is the advantage of an oral contrast agent for gallbladder imaging?

Oral cholecystography with Iocetamic Acid specifically evaluates gallbladder concentration function, which cannot be assessed by intravenous methods, providing additional diagnostic information.