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Ilaprazole

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Cat Number

API172152362

CAS Number

172152-36-2

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Product Detail

CAS Number

172152-36-2

Synonyms

IY-81149 noltec Iy 81149

Description

Ilaprazole is a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. A weak base, ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.

Molecular Formula

C19H18N4O2S

Molecular Weight

366.4

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