GEM-5

GEM-5

Cat Number
API2233543490
CAS Number
2233543-49-0

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CAS Number
2233543-49-0
Description
GEM-5, a gemcitabine-based conjugate incorporating a HIF-1α inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF-1α expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and curbs tumor growth.
Molecular Formula
C32H29F2N5O8
Molecular Weight
649.6
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