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Cat Number: API2359650192

TPX-0046

CAS Number

2359650-19-2

Description

TPX-0046 is a RET inhibitor designed to overcome resistance to Selpercatinib and Pralsetinib.

Molecular Formula

C21H21FN6O3

Molecular Weight

424.43

Smiles

FC=1C=C2CN3C=4C(=CN5C(N4)=C(C=N5)C(=O)NC[C@@H](C)OC2=NC1)O[C@]6([C@@]3(CCC6)[H])[H]

Purity

0.9907

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 2 mg/mL(4.71 mM), Sonication is recommended.

Relative Density

1.68 (Predicted)

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