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Cat Number: API1973403007

ARCC-4

CAS Number

1973403-00-7

Description

ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide and it is a low-nanomolar androgen receptor (AR) degrader based on PROTAC, with a DC50 of 5 nM. ARCC-4 effectively degrades clinically relevant AR mutants associated with antiandrogen therapy.

Molecular Formula

C53H56F3N7O7S2

Molecular Weight

1024.18

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Relative Density

1.39 (Predicted)

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INFORMATION