An ISO9001 Certified Supplier of Pharmaceutical Ingredients and Specialty Chemicals

Andrographolide

Inquiry

Cat Number

API5508587

CAS Number

5508-58-7

For research use only. We do not supply to patients.

For pharmaceutical-grade products or other inquiries, please contact our experts.

Product Detail

CAS Number

5508-58-7

Storage

Store at 4℃

Description

Andrographolide is a bicyclic diterpenoid lactone displaying antiviral, antiinflammatory, antiapoptotic, and antihyperglycemic properties. This chemical is an irreversible antagonist of NF-κB and prevents in vitro T cell activation. Andrographolide displays no effect on IκBa degradation but downregulates iNOS and Mac-1 expressions and ROS production. It has been shown to prevent endotoxin shock in mouse models and is reported to activate PI 3K/Akt pathways. Andrographolide is also an inhibitor of ERK.

Appearance

Powder

You Might Also Like