Iodohippurate Sodium I-131

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Cat Number

API881174

CAS Number

881-17-4

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Product Detail Description Customer Q&A

CAS Number

881-17-4

Molecular Formula

C9H7INNaO3

Molecular Weight

331.05

Smiles

C1=CC=C(C(=C1)C(=O)NCC(=O)[O-])[131I].[Na+]

General Description

Iodohippurate Sodium I-131 is a radiopharmaceutical in which iodine-131 is incorporated into the hippuric acid molecule. It is selectively excreted by the kidneys through glomerular filtration and tubular secretion.

Mechanism of Action

Iodohippurate Sodium I-131 is cleared from the bloodstream by the kidneys via glomerular filtration and proximal tubular secretion. The gamma emissions from I-131 decay are detected externally, generating renograms for functional assessment.

Application

Used in diagnostic renal function evaluation. Iodohippurate Sodium I-131 is indicated for renography, assessment of individual kidney function, detection of renal artery stenosis, and evaluation of urinary tract obstruction.

What diagnostic information does Iodohippurate I-131 provide compared to other renal imaging agents?

Iodohippurate I-131 specifically assesses tubular secretion and effective renal plasma flow, complementing agents that primarily evaluate glomerular filtration.