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5-Fluorouracil-13C,15N2

Inquiry

Cat Number

API1189423582

CAS Number

1189423-58-2

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Product Detail

CAS Number

1189423-58-2

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.

Molecular Formula

C4H3FN2O2

Molecular Weight

133.057

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