Warfarin Potassium

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Cat Number

API2610868

CAS Number

2610-86-8

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Product Detail Description Customer Q&A

CAS Number

2610-86-8

Synonyms

Potassium warfarin

Molecular Formula

C19H15KO4

Molecular Weight

346.4

Smiles

CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)[O-].[K+]

General Description

Warfarin Potassium is the potassium salt of warfarin, a coumarin-class oral anticoagulant. It functions as a vitamin K antagonist, interfering with the gamma-carboxylation of vitamin K-dependent clotting factors.

Mechanism of Action

Warfarin inhibits vitamin K epoxide reductase, preventing regeneration of reduced vitamin K required for gamma-carboxylation of clotting factors II, VII, IX, and X. This produces a gradual anticoagulant effect as existing factors are depleted.

Application

Used in the prevention and treatment of thromboembolic disorders. Warfarin Potassium is indicated for deep vein thrombosis, pulmonary embolism, atrial fibrillation stroke prevention, and anticoagulation after mechanical heart valve replacement.

What is the significance of the potassium salt form?

The potassium salt provides enhanced solubility and absorption characteristics compared to the free acid form, ensuring more consistent anticoagulation levels.