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Lumacaftor

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Cat Number

API936727058

CAS Number

936727-05-8

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Product Detail

CAS Number

936727-05-8

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).

Molecular Formula

C24H18F2N2O5

Molecular Weight

452.41

Smiles

CC1CCC(NC(=O)C2(CC2)C2CCC3OC(F)(F)OC3C2)NC1-C1CCCC(C1)C(O)=O

Relative Density

1.517

Purity

0.9972

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