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Umbralisib sulfate

Umbralisib sulfate

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Cat Number
API1532533757
CAS Number
1532533-75-7

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CAS Number
1532533-75-7
Synonyms
TGR-1202 sulfate; RP-5264 sulfate,TGR-1202 sulfate,RP-5264 sulfate
Description
Umbralisib (TGR-1202) sulfate, an orally active compound, serves as a potent, selective inhibitor targeting both PI3Kδ and casein kinase-1-ε (CK1ε), with EC50 values of 22.2 nM and 6.0 μM, respectively. It demonstrates unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL) and is applicable in the research of hematological malignancies.
Molecular Formula
C31H26F3N5O7S
Molecular Weight
669.63
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