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Umbralisib sulfate

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Cat Number

API1532533757

CAS Number

1532533-75-7

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Product Detail

CAS Number

1532533-75-7

Synonyms

TGR-1202 sulfate; RP-5264 sulfate,TGR-1202 sulfate,RP-5264 sulfate

Description

Umbralisib (TGR-1202) sulfate, an orally active compound, serves as a potent, selective inhibitor targeting both PI3Kδ and casein kinase-1-ε (CK1ε), with EC50 values of 22.2 nM and 6.0 μM, respectively. It demonstrates unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL) and is applicable in the research of hematological malignancies.

Molecular Formula

C31H26F3N5O7S

Molecular Weight

669.63

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