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Trifluridine

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Cat Number

API70008

CAS Number

70-00-8

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Product Detail

CAS Number

70-00-8

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Synonyms

NSC 529182, Trifluorothymidine, 5-Trifluorothymidine, NSC 75520, Viroptic, Trifluridina

Description

Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.

Molecular Formula

C10H11F3N2O5

Molecular Weight

296.2

Smiles

O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C(F)(F)F)C(=O)N1

Relative Density

1.646

Purity

0.9982

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