Description
Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (PI) HIV-1 isolates (IC50 of 66-410 nM).
Molecular Formula
C31H33F3N2O5S
Smiles
CCC[C@@]1(CCC2CCCCC2)CC(O)=C([C@H](CC)C2CCCC(NS(=O)(=O)C3CCC(CN3)C(F)(F)F)C2)C(=O)O1
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
Ethanol: 45.0 mg/mL (74.7 mM)DMSO: 180.0 mg/mL (298.7 mM ), Sonication is recommended.
Relative Density
1.313 (Predicted)