Talbutal

Inquiry

Cat Number

API115446

CAS Number

115-44-6

For research use only. We do not supply to patients.

For pharmaceutical-grade products or other inquiries, please contact our experts.

Product Detail Description Customer Q&A

CAS Number

115-44-6

Synonyms

5-(1-Methylpropyl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyriMidinetrione

Molecular Formula

C11H16N2O3

Molecular Weight

224.26

Smiles

CCC(C)C1(C(=O)NC(=O)NC1=O)CC=C

Appearance

White to off-white solid

Melting Point

108-110℃

Boiling Point

365.66℃

Relative Density

1.17

General Description

Talbutal is a short-acting barbiturate derivative of barbituric acid classified as a sedative-hypnotic. It produces CNS depression through enhancement of GABAergic neurotransmission.

Mechanism of Action

Talbutal binds to the barbiturate binding site on the GABA-A receptor complex, prolonging chloride channel opening duration and enhancing GABA-mediated inhibitory neurotransmission, producing sedation and hypnosis.

Application

Used for short-term management of insomnia. Talbutal is indicated for transient insomnia, preoperative sedation, and short-duration sedative requirements where rapid recovery is desired.

What distinguishes Talbutal from longer-acting barbiturates?

Talbutal is a short-acting barbiturate with rapid onset and brief duration, suitable for sleep induction without prolonged residual sedation or morning grogginess.