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Donafenib

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Cat Number

API1130115444

CAS Number

1130115-44-4

For research use only. We do not supply to patients.

For pharmaceutical-grade products or other inquiries, please contact our experts.

Product Detail

CAS Number

1130115-44-4

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Donafenib (Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).

Molecular Formula

C21H13ClD3F3N4O3

Molecular Weight

467.84

Smiles

[2H]C([2H])([2H])NC(=O)C1CC(OC2CCC(NC(=O)NC3CCC(Cl)C(C3)C(F)(F)F)CC2)CCN1

Relative Density

1.31

Purity

0.9988

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