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Sorafenib

Inquiry

Cat Number

API284461730

CAS Number

284461-73-0

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Product Detail

CAS Number

284461-73-0

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Sorafenib (Bay 43-9006) is a multikinase inhibitor that targets Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. It exhibits antitumor properties and can induce autophagy, apoptosis, and agonistic iron death.

Molecular Formula

C21H16ClF3N4O3

Molecular Weight

464.82

Smiles

O(C=1C=C(C(NC)=O)N=CC1)C2=CC=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2

Relative Density

1.455. Temperature:20.

Purity

0.9989

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