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Simmiparib

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Cat Number

API1551355464

CAS Number

1551355-46-4

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Product Detail

CAS Number

1551355-46-4

Description

Simmiparib (SMOCL-9112) is a novel and potent PARP1 and PARP2 inhibitor, a derivative of Olaparib.Simmiparib induces DNA double-strand breaks (DSBs) and cell cycle arrest in homologous recombination repair (HR)-deficient cells, thereby contributing to apoptosis.Simmiparib has been used for study Parkinson's disease, Alzheimer's disease, breast cancer, and melanoma.

Molecular Formula

C23H18F4N6O2

Molecular Weight

486.42

Smiles

CC1CN(CC2NNC(N12)C(F)(F)F)C(=O)C1CC(CC2N[NH]C(=O)C3CCCCC23)CCC1F

Purity

0.9951

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