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Ruxolitinib

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Cat Number

API941678495

CAS Number

941678-49-5

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Product Detail

CAS Number

941678-49-5

Synonyms

INCB018424 Ruxolitinib (INCB018424) (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile

Description

Used as the phosphate salt for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. It has a role as an antineoplastic agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.

Molecular Formula

C17H18N6

Molecular Weight

306.4

Appearance

Colorless oil

Melting Point

84-89℃

Boiling Point

592.6

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