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Rolapitant hydrochloride hydrate

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Cat Number

API914462923

CAS Number

914462-92-3

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Product Detail

CAS Number

914462-92-3

Description

Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP).

Molecular Formula

C25H29ClF6N2O3

Molecular Weight

554.95

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