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Rolapitant hydrochloride hydrate

Rolapitant hydrochloride hydrate

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Cat Number
API914462923
CAS Number
914462-92-3

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CAS Number
914462-92-3
Description
Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP).
Molecular Formula
C25H29ClF6N2O3
Molecular Weight
554.95
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