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Regorafenib monohydrate

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Cat Number

API1019206882

CAS Number

1019206-88-2

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Product Detail

CAS Number

1019206-88-2

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively.

Molecular Formula

C21H17ClF4N4O4

Molecular Weight

500.83

Smiles

O.CNC(=O)C1CC(OC2CCC(NC(=O)NC3CCC(Cl)C(C3)C(F)(F)F)C(F)C2)CCN1

Purity

0.9969

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