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Umbralisib R-enantiomer

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Cat Number

API1532533699

CAS Number

1532533-69-9

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Product Detail

CAS Number

1532533-69-9

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the inhibitors against other PI3K isoforms (A, β, and γ).

Molecular Formula

C31H24F3N5O3

Molecular Weight

571.55

Smiles

CC(C)OC1CCC(CC1F)-C1NN([C@H](C)C2OC3CCC(F)CC3C(=O)C2-C2CCCC(F)C2)C2NCNC(N)C12

Relative Density

1.43 (Predicted)

Purity

0.9561

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