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R-130823

R-130823

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Cat Number
API321344325
CAS Number
321344-32-5

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CAS Number
321344-32-5
Description
R-130823 is a ighly selective inhibition against mitogen-activated protein kinase p38alpha (IC50=22 nM). The release of tumor necrosis factor-alpha, interleukin-1beta, -6 and -8 was inhibited in lipopolysaccharide-stimulated human blood pretreated by R-130823 , with IC50 values of 0.089, 0.066, 0.95 and 0.16 microM, respectively.
Molecular Formula
C28H26FN3
Molecular Weight
423.52
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