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Ponatinib

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Cat Number

API943319708

CAS Number

943319-70-8

For research use only. We do not supply to patients.

For pharmaceutical-grade products or other inquiries, please contact our experts.

Product Detail

CAS Number

943319-70-8

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor with IC50 values of 0.37 nM (Abl), 1.1 nM (PDGFRα), 1.5 nM (VEGFR2), 2.2 nM (FGFR1), and 5.4 nM (Src).

Molecular Formula

C29H27F3N6O

Molecular Weight

532.56

Smiles

C(#CC1=CC(C(NC2=CC(C(F)(F)F)=C(CN3CCN(C)CC3)C=C2)=O)=CC=C1C)C=4N5C(=NC4)C=CC=N5

Relative Density

1.292

Purity

0.9974

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All our products are chemicals for research purposes only. We do not supply for human or veterinary applications.