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Ponatinib

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Cat Number

API943319708

CAS Number

943319-70-8

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Product Detail

CAS Number

943319-70-8

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor with IC50 values of 0.37 nM (Abl), 1.1 nM (PDGFRα), 1.5 nM (VEGFR2), 2.2 nM (FGFR1), and 5.4 nM (Src).

Molecular Formula

C29H27F3N6O

Molecular Weight

532.56

Smiles

C(#CC1=CC(C(NC2=CC(C(F)(F)F)=C(CN3CCN(C)CC3)C=C2)=O)=CC=C1C)C=4N5C(=NC4)C=CC=N5

Relative Density

1.292

Purity

0.9974

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