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Poloppin

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Cat Number

API683808788

CAS Number

683808-78-8

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Product Detail

CAS Number

683808-78-8

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Poloppin is a protein-protein interactions modulator of the mitotic polo-like kinases that acts by targeting mutant KRAS. It works synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells.

Molecular Formula

C20H15BrF3NO2

Molecular Weight

438.24

Relative Density

1.45 (Predicted)

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