Poloppin

Poloppin

Cat Number
API683808788
CAS Number
683808-78-8

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CAS Number
683808-78-8
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Description
Poloppin is a protein-protein interactions modulator of the mitotic polo-like kinases that acts by targeting mutant KRAS. It works synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells.
Molecular Formula
C20H15BrF3NO2
Molecular Weight
438.24
Relative Density
1.45 (Predicted)
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