Pipecuronium Bromide

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Cat Number

API52212029

CAS Number

52212-02-9

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Product Detail Description Customer Q&A

CAS Number

52212-02-9

EINECS

257-740-4

Storage

Under -20℃

Molecular Formula

C35H62Br2N4O4

Molecular Weight

762.7

Smiles

CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@@H]([C@]2(C[C@@H]1N4CC[N+](CC4)(C)C)C)CC[C@]5([C@H]3C[C@@H]([C@@H]5OC(=O)C)N6CC[N+](CC6)(C)C)C.[Br-].[Br-]

Appearance

White to off-white solid

Melting Point

262-264℃

General Description

Pipecuronium Bromide is a bisquaternary aminosteroid non-depolarizing neuromuscular blocking agent with a long duration of action and minimal histamine release or cardiovascular effects.

Mechanism of Action

Pipecuronium competitively occupies nicotinic acetylcholine receptors at the neuromuscular junction without receptor activation, preventing acetylcholine-mediated endplate depolarization and blocking skeletal muscle contraction.

Application

Used as an adjunct in surgical anesthesia. Pipecuronium Bromide is indicated for prolonged muscle relaxation during extended surgical procedures and mechanical ventilation in intensive care.

What advantage does Pipecuronium offer for prolonged surgeries?

Pipecuronium provides long-duration muscle relaxation with minimal cardiovascular effects and no histamine release, offering hemodynamic stability during extended procedures.