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Nedaplatin

Inquiry

Cat Number

API95734820

CAS Number

95734-82-0

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Product Detail

CAS Number

95734-82-0

Synonyms

Aqupla NSC 375101D azane;2-hydroxyacetic acid;platinum

Description

Nedaplatin is a second-generation cisplatin analogue with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucelophillic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death. This agent appears to be less nephrotoxic and neurotoxic compared to both cisplatin and carboplatin.

Molecular Formula

C2H10N2O3Pt

Molecular Weight

305.2

Appearance

White powder or crystalline powder

Standard

In-House

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