Nalpha-FMOC-L-Glutamine

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Cat Number

INT71989203

CAS Number

71989-20-3

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Product Detail Description Customer Q&A

CAS Number

71989-20-3

EINECS

276-254-3

Storage

2-8℃

Synonyms

FMOC-L-GLUTAMINE;FMOC-L-GLN-OH;FMOC-L-GLN

Molecular Formula

C20H20N2O5

Molecular Weight

368.38

Smiles

NC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

Appearance

White to off-white solid

Melting Point

220℃

Boiling Point

498.73℃

Relative Density

1.31

pKa

3.73

General Description

Nalpha-FMOC-L-Glutamine is an N-terminally protected L-glutamine residue, a fundamental component for building peptide chains via the Fmoc strategy.

Mechanism of Action

It functions as a source of L-glutamine during peptide elongation. The Fmoc group prevents the amino terminus from reacting prematurely, while the side-chain amide remains unprotected (or specifically protected in other versions) to maintain solubility and reactivity profiles.

Application

It is extensively utilized in the laboratory and industrial synthesis of physiologically active peptides and nutritional research molecules.