2,2,14,14-tetramethyl-8-oxopentadecanedioic acid

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Cat Number

INT413624712

CAS Number

413624-71-2

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Product Detail Description Customer Q&A

CAS Number

413624-71-2

Storage

Store at -20℃

Synonyms

Pentadecanedioic acid, 2,2,14,14-tetramethyl-8-oxo-

Molecular Formula

C19H34O5

Molecular Weight

342.47

Smiles

C(O)(=O)C(C)(C)CCCCCC(=O)CCCCCC(C)(C)C(O)=O

Appearance

White to off-white solid

Melting Point

82-83℃

Boiling Point

524.0℃

Relative Density

1.042

pKa

4.54

General Description

2,2,14,14-tetramethyl-8-oxopentadecanedioic acid is a long-chain keto-dicarboxylic acid characterized by a central ketone group and quaternary carbon centers at both alpha positions. This unique structure is designed to mimic fatty acids while offering enhanced metabolic resistance.

Mechanism of Action

It serves as a metabolically stable fatty acid analog. The presence of gem-dimethyl groups at the 2 and 14 positions inhibits standard beta-oxidation pathways, while the central ketone group provides a site for specific enzymatic interactions or further chemical modifications.

Application

It is a critical intermediate for the synthesis of advanced lipid-regulating agents and is extensively used in the research of treatments for hyperlipidemia and metabolic syndrome.