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Lapatinib

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Cat Number

API231277922

CAS Number

231277-92-2

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Product Detail

CAS Number

231277-92-2

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced or metastatic breast cancer with HER2 overexpression.

Molecular Formula

C29H26ClFN4O4S

Molecular Weight

581.06

Smiles

N(C=1C2=C(C=CC(=C2)C=3OC(CNCCS(C)(=O)=O)=CC3)N=CN1)C4=CC(Cl)=C(OCC5=CC(F)=CC=C5)C=C4

Relative Density

1.381 (Predicted)

Purity

0.9989

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