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Cat Number: API147076366

LaflunimusHR325

CAS Number

147076-36-6

Description

Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 μM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor. Laflunimusis an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH).

Molecular Formula

C15H13F3N2O2

Molecular Weight

310.27

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Relative Density

1.441

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