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Cat Number: API946075134

Isavuconazonium sulfate

CAS Number

946075-13-4

Description

Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), which catalyzes the demethylation of

Molecular Formula

C35H36F2N8O9S2

Molecular Weight

814.84

Smiles

OS([O-])(=O)=O.CNCC(=O)OCC1CCCNC1N(C)C(=O)OC(C)[N+]1CNN(C[C@@](O)([C@@H](C)C2NC(Cs2)-C2CCC(CC2)C#N)C2CC(F)CCC2F)C1

Purity

0.9942

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 50 mg/mL (61.36 mM)H2O: Insoluble