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Gefitinib dihydrochloride

Gefitinib dihydrochloride

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Cat Number
API184475567
CAS Number
184475-56-7

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CAS Number
184475-56-7
Description
Gefitinib dihydrochloride is a potent, selective, orally active EGFR tyrosine kinase inhibitor (IC50: 33 nM). Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth with an IC50 value of 54 nM and blocks EGFR autophosphorylation in EGF-stimulated tumor cells. Gefitinib dihydrochloride induces autophagy and apoptosis, and can be used in studies of cancer-related diseases such as lung and breast cancer.
Molecular Formula
C22H26Cl3FN4O3
Molecular Weight
519.82
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