An ISO9001 Certified Supplier of Pharmaceutical Ingredients and Specialty Chemicals

Gefitinib dihydrochloride

Inquiry

Cat Number

API184475567

CAS Number

184475-56-7

If you have any other questions, please contact our experts.

Product Detail

CAS Number

184475-56-7

Description

Gefitinib dihydrochloride is a potent, selective, orally active EGFR tyrosine kinase inhibitor (IC50: 33 nM). Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth with an IC50 value of 54 nM and blocks EGFR autophosphorylation in EGF-stimulated tumor cells. Gefitinib dihydrochloride induces autophagy and apoptosis, and can be used in studies of cancer-related diseases such as lung and breast cancer.

Molecular Formula

C22H26Cl3FN4O3

Molecular Weight

519.82

You Might Also Like