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Cat Number: API514363

Fludrocortisone acetate

CAS Number

514-36-3

Description

Fludrocortisone acetate (9α-Fludrocortisone acetate), a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and initiates transcription of glucocorticoid-responsive genes like lipocortins to inhibit phospholipase A2 (PLA2).

Molecular Formula

C23H31FO6

Molecular Weight

422.49

Smiles

[H][C@@]12CC[C@](O)(C(=O)COC(C)=O)[C@@]1(C)CC(=O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)CC[C@]12C

Purity

0.9803

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 45 mg/mL (106.51 mM)