Ethylestrenol

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Cat Number

API965902

CAS Number

965-90-2

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Product Detail Description Customer Q&A

CAS Number

965-90-2

Synonyms

Maxibolin;Orabolin;Duraboral

Molecular Formula

C20H32O

Molecular Weight

288.5

Smiles

CC[C@@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CCCC[C@H]34)C)O

General Description

Ethylestrenol is a synthetic anabolic-androgenic steroid (AAS) derived from estrane (19-nor testosterone), featuring a 17α-ethyl group. Unlike most anabolic steroids, it lacks a 17β-hydroxyl group in its basic structure, being a Δ4,9-estrenol, and has a relatively favorable anabolic-to-androgenic ratio.

Mechanism of Action

Ethylestrenol binds to androgen receptors and promotes anabolic gene transcription through androgen response elements. It is also metabolized to active androgenic and estrogenic metabolites, and may stimulate erythropoiesis through androgen receptor-mediated EPO pathway activation.

Application

Indicated for the treatment of osteoporosis and conditions requiring anabolic stimulation. Ethylestrenol is a 19-nor anabolic-androgenic steroid derived from estrane with a favorable anabolic-to-androgenic ratio, providing bone and muscle anabolic effects with reduced androgenic side effects.

What distinguishes Ethylestrenol from other 19-nor anabolic steroids?

Ethylestrenol lacks the 3-keto group present in most other 19-nor AAS, relying on metabolic conversion for activity, making it a distinctive reference for studying A-ring keto group roles in receptor binding.