Betrixaban

Inquiry

Cat Number

API330942057

CAS Number

330942-05-7

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Product Detail

CAS Number

330942-05-7

EINECS

682-459-2

Synonyms

PRT054021 Bevyxxa N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide

Description

Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity. Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE. VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients.

Molecular Formula

C23H22ClN5O3

Molecular Weight

451.9

Melting Point

200-212 ºC

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