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Cobimetinib

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Cat Number

API934660932

CAS Number

934660-93-2

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Product Detail

CAS Number

934660-93-2

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Synonyms

RG7420, XL518, GDC-0973

Description

Cobimetinib (GDC-0973) is a MEK1 inhibitor (IC50=4.2 nM) with selective and oral activity. Cobimetinib exhibits antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis.

Molecular Formula

C21H21F3IN3O2

Molecular Weight

531.31

Smiles

C(=O)(C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)N3C[C@](O)(C3)[C@@H]4CCCCN4

Relative Density

1.706

Purity

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