Chlormezanone

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Cat Number

API80773

CAS Number

80-77-3

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Product Detail Description Customer Q&A

CAS Number

80-77-3

EINECS

201-307-4

Storage

Room temperature

Synonyms

2-(4-Chlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide

Molecular Formula

C11H12ClNO3S

Molecular Weight

273.74

Smiles

CN1C(S(=O)(=O)CCC1=O)C2=CC=C(C=C2)Cl

Appearance

White to pale yellow solid

Melting Point

114℃

Boiling Point

534.5℃

Relative Density

1.22

General Description

Chlormezanone is a thiazine derivative classified as a sedative-hypnotic and anxiolytic agent with additional central muscle relaxant properties.

Mechanism of Action

Chlormezanone enhances GABA-mediated inhibitory neurotransmission in the central nervous system, producing anxiolytic and sedative effects while also depressing polysynaptic reflexes involved in muscle spasm.

Application

Used in the management of anxiety and musculoskeletal tension. Chlormezanone is indicated for anxiety states, tension headaches, and musculoskeletal spasm associated with anxiety.

How does Chlormezanone differ from benzodiazepine anxiolytics?

Chlormezanone provides combined anxiolytic and muscle relaxant effects through a non-benzodiazepine mechanism, potentially offering a different dependence profile.