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Cat Number: API835621084

Regorafenib mesylate

CAS Number

835621-08-4

Description

Regorafenib (BAY 73-4506) mesylate is an orally active multi-target receptor tyrosine kinase inhibitor, inhibiting VEGFR1/2/3 (IC50=13/4.2/46 nM), PDGFRβ (IC50: 22 nM), Kit (IC50: 7 nM), RET (IC50: 1.5 nM), and Raf-1 (IC50: 2.5 nM), with potent anti-tumor and anti-angiogenic effects.

Molecular Formula

C22H19ClF4N4O6S

Molecular Weight

578.92

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INFORMATION