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Regorafenib mesylate

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Cat Number
API835621084
CAS Number
835621-08-4

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CAS Number
835621-08-4
Description
Regorafenib (BAY 73-4506) mesylate is an orally active multi-target receptor tyrosine kinase inhibitor, inhibiting VEGFR1/2/3 (IC50=13/4.2/46 nM), PDGFRβ (IC50: 22 nM), Kit (IC50: 7 nM), RET (IC50: 1.5 nM), and Raf-1 (IC50: 2.5 nM), with potent anti-tumor and anti-angiogenic effects.
Molecular Formula
C22H19ClF4N4O6S
Molecular Weight
578.92
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