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Capmatinib xHCl

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Cat Number

API1029714893

CAS Number

1029714-89-3

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Product Detail

CAS Number

1029714-89-3

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM).

Molecular Formula

C23H18ClFN6O

Molecular Weight

448.89

Smiles

Cl.CNC(=O)C1CCC(CC1F)-C1CNC2NCC(CC3CCC4NCCCC4C3)N2N1

Purity

0.9924

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